Tramadol Side Effects
Tramadol is a synthetic drug primarily used as severe pain controller. It is an opioid-like drug and as well as other opioid medications, Tramadol has numerous benefits. It is also used as medication for treating restless leg syndrome and fibromyalgia, and it is effective in neurotransmitter release and reuptake. As well as other opioid drugs, Tramadol can potentially form habit, but in a less severe manner than other opioids.
Tramadol side effects may include gastrointestinal problems such as nausea, vomiting, diarrhea, constipation. These effects are common for opioid drugs because opioid mu receptors in the gastrointestinal tract increase stimulation of the circular muscles and decrease stimulation of the longitudinal muscles of colon wall. These effects lead to increased churning of the bowel content. Aside form gastrointestinal side effects, there are common effects that include somnolence, itching, sweating, flushing and dizziness.
Tramadol has some life threatening side effects and the seizures are the most important amongst them to be considered. Patients with a history of seizures should consult their physician and let him/her know about their seizures. There are some allergic side effects such as angioedema, severe rashes, toxic epidermal necrolysis, respiratory depression. Depression and suicidal tendencies are possible, also dependency and abuse, serotonin syndrom and orthostatic hypotension.
Tramadol is not recommended in pregnancy and lactation period. Even though it is considered to be less addicting than other opioid drugs, there is possibility of abusing. If taken in higher dosages than recommended, Tramadol can cause severe seizures that can even lead to death. This opioid analgesic has contraindications if used with alcohol, many MAO inhibitors and some HIV drugs.